In the Journal of Biomolecular Screening, a group of scientists published an article about using RapidFire and a HTS assay for sphingosine kinase inhibitors in blood.
The authors developed procedures to achieve homogeneous mixing of whole blood in 384-well plates and for a method requiring minimal manipulations to extract S1P from blood in 96- and 384-well plates prior to analyses using the RapidFire mass spectrometry system.
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